Nurse Jackie aired on Showtime from June 8, 2009, to June 28, 2015, running for seven seasons. The show followed Jackie Peyton (played by Edie Falco), a talented but deeply flawed ER nurse in New York City who struggled with a painkiller addiction while balancing her work, marriage, and personal life. Jackie was a complex character—caring and dedicated to her patients, but also manipulative and dishonest, doing whatever it took to keep her drug habit hidden.
The series didn’t shy away from showing the harsh realities of addiction and its consequences. Over the years, Jackie’s lies caught up with her, leading to the loss of her job, marriage, and many friendships. The show ended on a dramatic note, with Jackie overdosing in the hospital ER during the closing party for All Saints Hospital. The screen faded to black, leaving her fate intentionally ambiguous.
Despite the ending, Jackie’s story isn’t over. Amazon Prime Video is bringing the show back, but not as Nurse Jackie season 8. Instead, it will be a sequel series set 10 years later, following Jackie as she tries to rebuild her life without her nursing license.
Nurse Jackie ended after seven seasons because the story had reached its natural conclusion. The final season showed Jackie Peyton losing everything—her job, her marriage, and the trust of her closest allies.
She was fired from All Saints Hospital, arrested for drug possession, and forced into a diversion program where she could no longer work as a nurse. The show ended with her overdosing on heroin in the middle of the hospital’s farewell party. The screen cut to black, leaving her fate unknown.
A season 8 would have required picking up immediately after this moment, but the show was never intended to continue beyond that ending. Jackie’s addiction was the core of the series, and by the end, she had no more places to hide. The show had already explored her attempts at recovery, her relapses, and the damage she caused to those around her. A continuation would have been repetitive or forced a resolution that the show deliberately avoided.
Instead of Nurse Jackie season 8, Amazon Prime Video is developing a sequel series set ten years later. This approach allows for a fresh take on Jackie’s life without undoing the impact of the original ending.
The Nurse Jackie series finale, I Say a Little Prayer, brought Jackie Peyton’s story to a devastating but fitting end. All Saints Hospital was closing down, and the staff gathered for a farewell party. Jackie, who had spent years deceiving everyone around her, had convinced them she was finally clean. In reality, she was still using.
Throughout the episode, Jackie tied up loose ends. She had a final conversation with Kevin, who seemed to have fully moved on from her. She spoke with Akalitus, who had lost all trust in her but still cared enough to warn her about her choices.
She asked Zoey to follow her to Bellevue Hospital, where she had secured a new job, but Zoey refused. After years of looking up to Jackie, Zoey realized she needed to move on.
Eddie was facing prison time for supplying drugs, a consequence of his unwavering loyalty to Jackie. Instead of trying to fix things, she let him take the fall. As the party went on, Jackie walked into the bathroom and snorted three lines of heroin—a final act of self-destruction.
She walked back out, took off her ID badge and stethoscope, then collapsed on the floor. The hospital staff rushed to her side. Zoey tried to revive her, repeating, “You’re good, Jackie, you’re good.” The screen cut to black, leaving Jackie’s fate unknown.
Showrunner Clyde Phillips later said the ending was meant to be open-ended. Some believe Jackie died, while others think she survived but hit rock bottom once again. The final scene was not about redemption. It was about addiction, its consequences, and the reality that some people never truly escape it.
Nurse Jackie episodes are available on Paramount+ for streaming.